This study aims to analyze the impact of information technology governance on the quality of e-health services in public hospitals, highlighting the mediating role of digital human competencies. It relies on the conceptuel framework of IT governance and its core principles as a strategic mechanism to ensure the optimal and secure utilization of technology, thereby aligning tech infrastructure with institutional performance. Furthermore, the study addresses digital human competencies across various dimensions, emphasizing the necessity of developing them in accordance with digital transformation requirements in the healthcare sector. The findings highlight the key role of continuous training, organisationnel support, and facilitating conditions in enhancing digital readiness and empowering medical and administrative staff to effectively deploy modern health technologies. Additionally, it underscores the importance of digital leadership and organizational culture in fostering an environment conducive to digital learning. Finally, the study examines the dimensions of e-health service quality—specifically speed, reliability, responsiveness, and beneficiary satisfaction—positing that IT governance directly enhances service quality by establishing clear policies and management frameworks for both technical and human resources.